This episode featured guests Martin Sheen, comedian Ed Byrne, and musical guests Will.i.am and Cheryl Cole (“Heartbreaker”). On this episode, Sheen, former president of The West Wing, announced support for Senator Barack Obama in the 2008 presidential campaign: “It’s unfortunate that they’re beating each other up. I haven’t made a proper claim, maybe I should do it here, I’m an Obama supporter. But you mustn’t reveal it yet, Bill Clinton loved The West Wing and he still calls me his President, so I have to be careful for just a while longer.”